Overview
The toxicological evaluation is designed to provide students with an opportunity to do their own risk evaluation of an assigned compound. Each student will be assigned a compound and will assess where or not the compound is poses risk to biological systems (humans, animals, and environment). The assessment should include the following provided the information is available:
- Description of the compound (what is it)
- Location (where is it found; naturally occurring or synthetic)
- Summary of a case study (eg. poisoning, ecological disaster, historical use)
- Uses (eg. therapeutic, agricultural)
- Toxicodynamic properties (what does it do)
- Toxicokinetic properties (ADME)
- Mechanism of toxicity (if known)
- Sensitive populations
- Treatment
- Federal Regulations
- Reference exposure doses (oral or inhalation;
see EPA, FDA, NIOSH, OSHA) - Your assessment on the potential risk to humans, animals and/or the environment
The assessment should be concise (please no more than 5 pages). All information must be sighted from a peer reviewed source (acceptable sources are listed below in the Recommended Reading Section). Each student will give a brief presentation (chalk talk NO PowerPoint or other media) on the last day of class.