There has been considerable controversy about the nature of cells involved in regeneration of an organ or part of an organ. It has often been argued that nonspecialized "reserve" cells (those not very far along on a given differentiation pathway) are the source of cells for new issues, and that overtly differentiated cells cannot change to form another cell type. Using the example of limb regression in salamanders, propose an experiment or approach to evaluate this hypothesis.
Format of the Lab Report
The lab report must be at least 3 pages in length; a 12-point font must be used; it must be double spaced; and citations must be included within the text of your document as well as in a separate Works Cited Section. The Works Cited Section must be a separate section. You may ask me for advice well before the submission deadline. Please note that asking me for advice is only to confirm whether or not you are on the right track. I will not grade your lab assignment prior to your submission on Canvas.
Your lab report must accurately document the sources from which your material was gathered. Any time you describe an individual's data or other experimental results, paraphrase an author(s), or describe data from the textbook, you must credit that individual. Direct quotes should not be used, instead paraphrase the statement and include the appropriate citation(s). It is incorrect to include just a single citation at the end of a paragraph for the following reasons: 1) a citation only refers to the sentence that directly preceded it; and 2) the other data or ideas stated in the paragraph are now not cited. Be careful and familiarize yourself with Montclair State's policy on plagiarism (see course syllabus). When in doubt, always cite your sources. The proper citation of your sources is of paramount importance, and lab reportssubmitted without proper documentation will have a significant amount of points deducted.
You must support your assertions with citations from the primary literature.
Rubric
Limb Regeneration Lab Rubric
| Criteria | Ratings | Pts | |||
|---|---|---|---|---|---|
This criterion is linked to a Learning OutcomeBackground information on limb regeneration |
| 20 pts | |||
This criterion is linked to a Learning OutcomeProposed experiment/approach to test whether "reserve" cells or differentiated cells have the ability to transform into another cell type(s) |
| 50 pts | |||
This criterion is linked to a Learning OutcomeDescription of criterion |
| 30 pts | |||
Total Points: 100 |