Overview
Read the following article
https://cen.acs.org/pharmaceuticals/drug-discovery/Covalent-drugs-fringe-field-fashionable/98/i43
Answer the following prompts.
How is a reversible drug different than a covalent drug?
Why are covalent drugs becoming more of a topic?
How can a covalent drug be intentionally designed?
What was the significance of Ibrutiniv? Why was it significant in the consideration of the potential for covalent drugs?
What is the potential of a KRAS inhibitor? How is it a covalent drug and why does it have to be?
What did you learn from the article and what is your one most important take away from reading it?