Overview
Case Study Scenario: Reperfusion Injury
A 68 year male suffered from coronary artery disease that required bypass surgery. During the surgery the heart muscle was deprived of blood flow for an extended period of time. Upon reperfusion of the heart muscle the surgeons were anticipating further damage or injury to the heart muscle tissue. At times, the return of blood flow to tissue that has previously been deprived of a blood supply due to ischemia or hypoxemia results in further damage or injury to that tissue. This is referred to as reperfusion injury.
Instruction:
- Give an overview of the diagnosis including risk factors and how they cause or contribute
to adaptation or pathogenesis. - Give an in-depth discussion of the pathophysiology of your diagnosis as it occurs over time; include signs, symptoms, diagnostic studies and the underlying pathophysiologic process causing these signs and symptoms. Support this pathophysiology with high level evidence.
- Summarize treatments and outcomes in terms of pathophysiologic alterations.
- Include a discussion of the symptoms that your patient is exhibiting and discuss
treatments specifically aimed for your patient. - Support your case discussion with current (in the past 5 years) high level evidence. Patient information portals, disease association websites and other resources such as Up-to-date, Epocrates, Medscape, Mayo Clinic are not considered high levels of evidence and should be avoided for your presentations. While use of the course textbooks is permitted, a minimum of 3 high level citations outside of the course text is required.
- Length: A minimum of 350 words, not including references
- Citations: At least three high-level scholarly reference in APA from within the last 5 years