Overview
Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.
For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
To Prepare:
- Review the case study posted in “Announcements” by your Instructor for this Assignment
- Review the information provided and answer questions posed in the case study
- When recommending a medication, write out a complete prescription for the medication
- Whenever possible, use clinical practice guidelines in developing your answers when possible
- Include at least three references to support your answer and cite them in APA format.
WEEK 7 ASSIGNMENT (covers weeks 7 & 8)
SCENARIO 1
What are the errors in the following prescriptions (5 total)? Rewrite each prescription correctly. What is each medication classification? What is the mechanism of action (MOA)?
· acamprosate 666 mg take 2 tablets PO TID #180 0 RF
· lisdexamfetamine (Vyvanse) 30 mg PO QAM #30 1 RF
· naltrexone (Vivitrol) ER 380 mg IM inject once weekly #1 3 RF
· infliximab (Humira) 40 mg SQ inject every other week #2 1 RF
· colchicine 0.6 mg PO every 2 hours for acute gout flare #6 0 RF
SCENARIO 2
When a person uses nicotine, it causes temporary feelings of relaxation, well-being, focus, and attention. Nicotine binds to nicotinic receptors in the brain, augmenting the release of numerous neurotransmitters including dopamine, norepinephrine, serotonin, acetylcholine, and glutamate. Patients may self-medicate ADHD, anxiety and depression by smoking. Is there a medication that could treat ADHD, anxiety, depression and provide smoking cessation? Write a complete medication order for this medication. Include patient monitoring and counseling. Does the patient need to quit smoking before starting treatment?
SCENARIO 3
Zolpidem has a half-life of 3 hours. If a patient takes 10 mg at 21:00, what will the blood level be at 06:00? Name 3 antidepressants/antipsychotics you might prescribe for patients with co-existing depression and insomnia. What is their MOA? Include complete medication orders and patient monitoring for each of the 3 medications.
SCENARIO 4
JL is a 50-year-old female presenting for medication refills. She has no recent lab work, but reports fatigue and occasional dizziness. Current meds: metformin 1000 mg daily, Janumet 50/1000 mg BID, paroxetine 20 mg daily, venlafaxine ER 150 mg daily, buspirone 5 mg TID PRN, valacyclovir 500 mg daily, dicyclomine 10 mg po QID PRN. She is unsure of her A1c or blood pressure. How would you assess and improve her regimen? What monitoring is needed? List 5 possible disease states based on her medications.
Note on Assignment Attempts
Students are expected to review their work and submissions of work carefully prior to due dates. Unless otherwise approved by the faculty, students are allowed one submission of graded work per assignment. While the classroom allows for multiple submissions, once an assignment is graded, submissions will no longer be accepted unless approved by the faculty. If an assignment is submitted prior to the assignment deadline and has not yet been graded, then students may submit a revised assignment prior to the assignment deadline. Once the deadline has passed, resubmission is not permitted.
Note: If you do not purchase Lecturio, please consult these resources for this week.
- Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.). Elsevier.
- Chapter 24, “Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics” (pp. 183–194)
- Chapter 32, “Substance Use Disorders I: Basic Considerations” (pp. 255a–259)
- Chapter 33, “Substance Use Disorders II: Alcohol” (pp. 260–266)
- Chapter 34, “Substance Use Disorders III: Nicotine and Smoking” (pp. 267–272)
- Chapter 35, “Substance Use Disorders IV: Major Drugs of Abuse Other Than Alcohol and Nicotine” (pp. 273–284)
- Chapter 57, “Cyclooxygenase Inhibitors: Nonsteroidal Antiinflammatory Drugs and Acetaminophen” (pp. 493–503)
- Chapter 59, “Drug Therapy of Rheumatoid Arthritis” (pp. 513a–527)
- Chapter 60, “Drug Therapy for Gout” (pp. 528–536)